COVID-19 and emerging viral infections: The case for interferon lambda.
Identifieur interne : 000940 ( Main/Exploration ); précédent : 000939; suivant : 000941COVID-19 and emerging viral infections: The case for interferon lambda.
Auteurs : Ludmila Prokunina-Olsson [États-Unis] ; Noémie Alphonse [Royaume-Uni] ; Ruth E. Dickenson [Royaume-Uni] ; Joan E. Durbin [États-Unis] ; Jeffrey S. Glenn [États-Unis] ; Rune Hartmann [Danemark] ; Sergei V. Kotenko [États-Unis] ; Helen M. Lazear [États-Unis] ; Thomas R. O'Brien [États-Unis] ; Charlotte Odendall [Royaume-Uni] ; Olusegun O. Onabajo [États-Unis] ; Helen Piontkivska [États-Unis] ; Deanna M. Santer [Canada] ; Nancy C. Reich [États-Unis] ; Andreas Wack [Royaume-Uni] ; Ivan Zanoni [États-Unis]Source :
- The Journal of experimental medicine [ 1540-9538 ] ; 2020.
Descripteurs français
- KwdFr :
- MESH :
- métabolisme : Infections à coronavirus, Interférons, Pneumopathie virale.
- Humains, Pandémies, Pénétration virale.
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Interferons.
- metabolism : Coronavirus Infections, Pneumonia, Viral.
- physiology : Betacoronavirus.
- Humans, Pandemics, Virus Internalization.
Abstract
With the first reports on coronavirus disease 2019 (COVID-19), which is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the scientific community working in the field of type III IFNs (IFN-λ) realized that this class of IFNs could play an important role in this and other emerging viral infections. In this Viewpoint, we present our opinion on the benefits and potential limitations of using IFN-λ to prevent, limit, and treat these dangerous viral infections.
DOI: 10.1084/jem.20200653
PubMed: 32289152
Affiliations:
- Canada, Danemark, Royaume-Uni, États-Unis
- Angleterre, Californie, Caroline du Nord, Grand Londres, Maryland, Massachusetts, New Jersey, Pennsylvanie, État de New York
- Londres
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Le document en format XML
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Dickenson</name><affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Durbin, Joan E" sort="Durbin, Joan E" uniqKey="Durbin J" first="Joan E" last="Durbin">Joan E. 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Lazear</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, NC.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill</wicri:cityArea></affiliation></author><author><name sortKey="O Brien, Thomas R" sort="O Brien, Thomas R" uniqKey="O Brien T" first="Thomas R" last="O'Brien">Thomas R. 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Santer</name><affiliation wicri:level="1"><nlm:affiliation>Li Ka Shing Institute of Virology and Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Li Ka Shing Institute of Virology and Department of Medical Microbiology and Immunology, University of Alberta, Edmonton</wicri:regionArea><wicri:noRegion>Edmonton</wicri:noRegion></affiliation></author><author><name sortKey="Reich, Nancy C" sort="Reich, Nancy C" uniqKey="Reich N" first="Nancy C" last="Reich">Nancy C. Reich</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology & Immunology, Stony Brook University, Stony Brook, NY.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Microbiology & Immunology, Stony Brook University, Stony Brook</wicri:cityArea></affiliation></author><author><name sortKey="Wack, Andreas" sort="Wack, Andreas" uniqKey="Wack A" first="Andreas" last="Wack">Andreas Wack</name><affiliation wicri:level="3"><nlm:affiliation>Immunoregulation Laboratory, Francis Crick Institute, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Immunoregulation Laboratory, Francis Crick Institute, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Zanoni, Ivan" sort="Zanoni, Ivan" uniqKey="Zanoni I" first="Ivan" last="Zanoni">Ivan Zanoni</name><affiliation wicri:level="2"><nlm:affiliation>Division of Immunology, Division of Gastroenterology, Harvard Medical School, Boston Children's Hospital, Boston, MA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Division of Immunology, Division of Gastroenterology, Harvard Medical School, Boston Children's Hospital, Boston</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32289152</idno><idno type="pmid">32289152</idno><idno type="doi">10.1084/jem.20200653</idno><idno type="wicri:Area/PubMed/Corpus">000165</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000165</idno><idno type="wicri:Area/PubMed/Curation">000165</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000165</idno><idno type="wicri:Area/PubMed/Checkpoint">000745</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000745</idno><idno type="wicri:Area/Ncbi/Merge">003A20</idno><idno type="wicri:Area/Ncbi/Curation">003A20</idno><idno type="wicri:Area/Ncbi/Checkpoint">003A20</idno><idno type="wicri:Area/Main/Merge">000940</idno><idno type="wicri:Area/Main/Curation">000940</idno><idno type="wicri:Area/Main/Exploration">000940</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">COVID-19 and emerging viral infections: The case for interferon lambda.</title><author><name sortKey="Prokunina Olsson, Ludmila" sort="Prokunina Olsson, Ludmila" uniqKey="Prokunina Olsson L" first="Ludmila" last="Prokunina-Olsson">Ludmila Prokunina-Olsson</name><affiliation wicri:level="2"><nlm:affiliation>Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Alphonse, Noemie" sort="Alphonse, Noemie" uniqKey="Alphonse N" first="Noémie" last="Alphonse">Noémie Alphonse</name><affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Dickenson, Ruth E" sort="Dickenson, Ruth E" uniqKey="Dickenson R" first="Ruth E" last="Dickenson">Ruth E. Dickenson</name><affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Durbin, Joan E" sort="Durbin, Joan E" uniqKey="Durbin J" first="Joan E" last="Durbin">Joan E. Durbin</name><affiliation wicri:level="2"><nlm:affiliation>Department of Pathology, Laboratory Medicine and Immunology, Newark, NJ.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">New Jersey</region></placeName><wicri:cityArea>Department of Pathology, Laboratory Medicine and Immunology, Newark</wicri:cityArea></affiliation></author><author><name sortKey="Glenn, Jeffrey S" sort="Glenn, Jeffrey S" uniqKey="Glenn J" first="Jeffrey S" last="Glenn">Jeffrey S. Glenn</name><affiliation wicri:level="2"><nlm:affiliation>Departments of Medicine and Microbiology & Immunology, Stanford University School of Medicine, and Palo Alto Veterans Administration, Palo Alto, CA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Departments of Medicine and Microbiology & Immunology, Stanford University School of Medicine, and Palo Alto Veterans Administration, Palo Alto</wicri:cityArea></affiliation></author><author><name sortKey="Hartmann, Rune" sort="Hartmann, Rune" uniqKey="Hartmann R" first="Rune" last="Hartmann">Rune Hartmann</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Molecular Biology and Genetics, Aarhus University, Aarhus</wicri:regionArea><wicri:noRegion>Aarhus</wicri:noRegion></affiliation></author><author><name sortKey="Kotenko, Sergei V" sort="Kotenko, Sergei V" uniqKey="Kotenko S" first="Sergei V" last="Kotenko">Sergei V. Kotenko</name><affiliation wicri:level="2"><nlm:affiliation>Center for Immunity and Inflammation, Rutgers New Jersey Medical School, Rutgers Biomedical and Health Sciences, Newark, NJ.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">New Jersey</region></placeName><wicri:cityArea>Center for Immunity and Inflammation, Rutgers New Jersey Medical School, Rutgers Biomedical and Health Sciences, Newark</wicri:cityArea></affiliation></author><author><name sortKey="Lazear, Helen M" sort="Lazear, Helen M" uniqKey="Lazear H" first="Helen M" last="Lazear">Helen M. Lazear</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, NC.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill</wicri:cityArea></affiliation></author><author><name sortKey="O Brien, Thomas R" sort="O Brien, Thomas R" uniqKey="O Brien T" first="Thomas R" last="O'Brien">Thomas R. O'Brien</name><affiliation wicri:level="2"><nlm:affiliation>Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Odendall, Charlotte" sort="Odendall, Charlotte" uniqKey="Odendall C" first="Charlotte" last="Odendall">Charlotte Odendall</name><affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Onabajo, Olusegun O" sort="Onabajo, Olusegun O" uniqKey="Onabajo O" first="Olusegun O" last="Onabajo">Olusegun O. Onabajo</name><affiliation wicri:level="2"><nlm:affiliation>Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Piontkivska, Helen" sort="Piontkivska, Helen" uniqKey="Piontkivska H" first="Helen" last="Piontkivska">Helen Piontkivska</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biological Sciences, School of Biomedical Sciences, Kent State University, Kent, PA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Department of Biological Sciences, School of Biomedical Sciences, Kent State University, Kent</wicri:cityArea></affiliation></author><author><name sortKey="Santer, Deanna M" sort="Santer, Deanna M" uniqKey="Santer D" first="Deanna M" last="Santer">Deanna M. Santer</name><affiliation wicri:level="1"><nlm:affiliation>Li Ka Shing Institute of Virology and Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Li Ka Shing Institute of Virology and Department of Medical Microbiology and Immunology, University of Alberta, Edmonton</wicri:regionArea><wicri:noRegion>Edmonton</wicri:noRegion></affiliation></author><author><name sortKey="Reich, Nancy C" sort="Reich, Nancy C" uniqKey="Reich N" first="Nancy C" last="Reich">Nancy C. Reich</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology & Immunology, Stony Brook University, Stony Brook, NY.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Microbiology & Immunology, Stony Brook University, Stony Brook</wicri:cityArea></affiliation></author><author><name sortKey="Wack, Andreas" sort="Wack, Andreas" uniqKey="Wack A" first="Andreas" last="Wack">Andreas Wack</name><affiliation wicri:level="3"><nlm:affiliation>Immunoregulation Laboratory, Francis Crick Institute, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Immunoregulation Laboratory, Francis Crick Institute, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Zanoni, Ivan" sort="Zanoni, Ivan" uniqKey="Zanoni I" first="Ivan" last="Zanoni">Ivan Zanoni</name><affiliation wicri:level="2"><nlm:affiliation>Division of Immunology, Division of Gastroenterology, Harvard Medical School, Boston Children's Hospital, Boston, MA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Division of Immunology, Division of Gastroenterology, Harvard Medical School, Boston Children's Hospital, Boston</wicri:cityArea></affiliation></author></analytic><series><title level="j">The Journal of experimental medicine</title><idno type="eISSN">1540-9538</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Betacoronavirus (physiology)</term><term>Coronavirus Infections (metabolism)</term><term>Humans</term><term>Interferons (metabolism)</term><term>Pandemics</term><term>Pneumonia, Viral (metabolism)</term><term>Virus Internalization</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Humains</term><term>Infections à coronavirus (métabolisme)</term><term>Interférons (métabolisme)</term><term>Pandémies</term><term>Pneumopathie virale (métabolisme)</term><term>Pénétration virale</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Interferons</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Infections à coronavirus</term><term>Interférons</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Pandemics</term><term>Virus Internalization</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Humains</term><term>Pandémies</term><term>Pénétration virale</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">With the first reports on coronavirus disease 2019 (COVID-19), which is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the scientific community working in the field of type III IFNs (IFN-λ) realized that this class of IFNs could play an important role in this and other emerging viral infections. In this Viewpoint, we present our opinion on the benefits and potential limitations of using IFN-λ to prevent, limit, and treat these dangerous viral infections.</div></front></TEI><affiliations><list><country><li>Canada</li><li>Danemark</li><li>Royaume-Uni</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Californie</li><li>Caroline du Nord</li><li>Grand Londres</li><li>Maryland</li><li>Massachusetts</li><li>New Jersey</li><li>Pennsylvanie</li><li>État de New York</li></region><settlement><li>Londres</li></settlement></list><tree><country name="États-Unis"><region name="Maryland"><name sortKey="Prokunina Olsson, Ludmila" sort="Prokunina Olsson, Ludmila" uniqKey="Prokunina Olsson L" first="Ludmila" last="Prokunina-Olsson">Ludmila Prokunina-Olsson</name></region><name sortKey="Durbin, Joan E" sort="Durbin, Joan E" uniqKey="Durbin J" first="Joan E" last="Durbin">Joan E. Durbin</name><name sortKey="Glenn, Jeffrey S" sort="Glenn, Jeffrey S" uniqKey="Glenn J" first="Jeffrey S" last="Glenn">Jeffrey S. Glenn</name><name sortKey="Kotenko, Sergei V" sort="Kotenko, Sergei V" uniqKey="Kotenko S" first="Sergei V" last="Kotenko">Sergei V. Kotenko</name><name sortKey="Lazear, Helen M" sort="Lazear, Helen M" uniqKey="Lazear H" first="Helen M" last="Lazear">Helen M. Lazear</name><name sortKey="O Brien, Thomas R" sort="O Brien, Thomas R" uniqKey="O Brien T" first="Thomas R" last="O'Brien">Thomas R. O'Brien</name><name sortKey="Onabajo, Olusegun O" sort="Onabajo, Olusegun O" uniqKey="Onabajo O" first="Olusegun O" last="Onabajo">Olusegun O. Onabajo</name><name sortKey="Piontkivska, Helen" sort="Piontkivska, Helen" uniqKey="Piontkivska H" first="Helen" last="Piontkivska">Helen Piontkivska</name><name sortKey="Reich, Nancy C" sort="Reich, Nancy C" uniqKey="Reich N" first="Nancy C" last="Reich">Nancy C. Reich</name><name sortKey="Zanoni, Ivan" sort="Zanoni, Ivan" uniqKey="Zanoni I" first="Ivan" last="Zanoni">Ivan Zanoni</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Alphonse, Noemie" sort="Alphonse, Noemie" uniqKey="Alphonse N" first="Noémie" last="Alphonse">Noémie Alphonse</name></region><name sortKey="Dickenson, Ruth E" sort="Dickenson, Ruth E" uniqKey="Dickenson R" first="Ruth E" last="Dickenson">Ruth E. Dickenson</name><name sortKey="Odendall, Charlotte" sort="Odendall, Charlotte" uniqKey="Odendall C" first="Charlotte" last="Odendall">Charlotte Odendall</name><name sortKey="Wack, Andreas" sort="Wack, Andreas" uniqKey="Wack A" first="Andreas" last="Wack">Andreas Wack</name></country><country name="Danemark"><noRegion><name sortKey="Hartmann, Rune" sort="Hartmann, Rune" uniqKey="Hartmann R" first="Rune" last="Hartmann">Rune Hartmann</name></noRegion></country><country name="Canada"><noRegion><name sortKey="Santer, Deanna M" sort="Santer, Deanna M" uniqKey="Santer D" first="Deanna M" last="Santer">Deanna M. Santer</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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